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After adjusting for other factors, significant differences in the enzymatic activities of CYP19A1 ( p = 0.001) and CYP1A1 ( p = 0.002) were still observed between the study groups, although there was no significant effect on placental GST activity

MELANOCYTE MELANIN TYROSINE TYROSINASE 2 EUMELANIN - PHEOMELANIN GLUTATHIONE 3 1.) (MELANIN) 2.) (PHEOMELANIN) (EUMELANIN) 3.) COFACTOR COENZYME AMINO ACID 3 GLYCINE, GLUTAMINE, CYSTEINE N-ACETYL CYSTEINE(NAC) L- CYSTEINE VITAMIN B6, VITAMIN B12, FOLIC ACID CYSTEINE VITAMIN B3(NADPH) COFACTOR GLUTATHIONE VITAMIN C VITAMIN E ALPHA LIPOIC ACID(ALA) GLUTATHIONE () SELENIUM RECDUCED FORM SELENIUM COFACTOR GLUTATHIONE PEROXIDASE () ENCAPSULATION SUBLINGUAL GLUTATHIONE . GLUTATHIONE MAX DOSE 250 mg 30 20 - 40 ./ (.)/ 500 ./ 2 - 1-3 - 3-6 - 6-12 - 2 () - - UV UV - () - SIDE EFFECT - () DETOX SIDE EFFECT GLUTATHIONE TYROSINASE REDUCED FORM R&D () OEM (NPD) OEM

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